HEPATOPROTECTIVE EVALUATION OF EPALTES DIVARICATA (L.) CASS. WHOLE PLANT EXTRACTS AGAINST PARACETAMOL-INDUCED HEPATOTOXICITY IN RATS
نویسندگان
چکیده
منابع مشابه
Hepatoprotective Activity of Tabernaemontana Divaricata Linn. against Paracetamol Induced Hepatotoxicity in Rats
The present study was conducted to evaluate the hepatoprotective activity of hydroalcoholic extract of Tabernaemontana divaricata Linn.against paracetamol induced liver damage in rats. The hydroalcoholic extract of Tabernamontana divaricata Linn. (600mg/kg) was administered orally to the animals with hepatotoxicity induced by paracetamol (3gm/kg). Silymarin (25mg/kg) was given as reference stan...
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Liaqat HUSSAIN, Javaria IKRAM, Kanwal REHMAN, Muhammad TARIQ, Muhammad IBRAHIM, Muhammad Sajid Hamid AKASH* College of Pharmacy, Government College University Faisalabad, Faisalabad, Pakistan Institute of Pharmacology, Toxicology, and Biochemical Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P.R. China Department of Applied Chemistry, Faculty of Science and T...
متن کاملHepatoprotective effect of Epaltes divaricata extract on carbon tetrachloride induced hepatotoxicity in mice.
BACKGROUND & OBJECTIVES Epaltes divaricata is widely used in Sri Lanka as an Ayurvedic medicine. In the present study the hepatoprotective and antioxidative effects of an aqueous extract of E. divaricata plant (Family-Compositae) were investigated against carbon tetrachloride induced hepatocellular injury in mice. METHODS Healthy male mice (30-35 g body weight, 6-8 wk old) were used. A single...
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Objective: Ethanol extract of Cajanus cajan (L.) Millsp. (Pigeonpea) leaves (ECC) was investigated for its hepatoprotective activity. Methods: Different groups of Wistar albino rats were administered with paracetamol (500 mg/kg, p.o., once daily for 7 days) for induction of hepatotoxicity. ECC (100, 200 and 300 mg/kg/day) and silymarin (25 mg/kg/day) were administered to the paracetamol induced...
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Background & Aim: The human body has the liver as one of its largest organs. It serves as the major site for metabolism and excretion. Injury to the liver or impairment of its functions may complicate one’s health and therefore, constitutes one of the serious public health challenges. The ethanol seed extract of Citrus paradisi Macfad (CPE) was carried out to evaluate ...
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ژورنال
عنوان ژورنال: International Journal of Pharmacy and Pharmaceutical Sciences
سال: 2016
ISSN: 0975-1491
DOI: 10.22159/ijpps.2016v8i12.14951